Platelet-Derived Exosomes
Platelet-Derived Exosomes: A Key Part of Autologous Therapy
Platelets are a vital part of regenerative medicine because of their direct role in blood clotting and tissue repair. These cell fragments are rich sources of bioactive molecules. When activated, they release a powerful mix of growth factors and exosomes that start the healing process, making them a primary target for autologous treatments.
Why Standard PRP Methods Fall Short
While the goal of PRP is to concentrate platelets, common preparation methods have two key weaknesses that limit their clinical results:
1. Inconsistent and Variable Results:
PRP preparation is known for being unstandardized. The final platelet concentration changes significantly based on the equipment, the protocol, and the patient. This makes it impossible to administer a consistent, predictable therapeutic dose.
2. Wasting Valuable Components:
This is the most critical weakness. In isolating the “platelet-rich” fraction, nearly all standard methods require discarding the platelet-poor plasma (PPP). This discarded fluid contains billions of valuable exosomes and other growth factors that play a direct role in healing. Discarding the PPP means throwing away a major part of the treatment’s potential.
Regenerative Profile
The exosmart™ system was built to solve the core problems of traditional PRP. We provide a method to use the potential of not just platelets, but the entire regenerative profile of a patient’s own blood.
Our technology ensures:
- Total Plasma Processing: We are unique in processing both the platelet-rich and platelet-poor plasma. Nothing is thrown away. This ensures the complete population of exosomes—both from platelets and from the plasma itself—is captured.
- A More Potent Combination: Our filtration system concentrates all key therapeutic parts. The final product is a potent combination of platelets, a high number of exosomes, and the full spectrum of plasma growth factors, all working together.
- Standardized, Predictable Results: Our validated, automated process removes the variability of manual PRP preparation. It delivers a high-quality product you can rely on, every time.
The exosmart™ Product: A Superior Therapeutic Material
- High Concentration: Up to 3.0 x 10¹³ particles/mL.
- Validated Purity: Meets MISEV2023 guidelines with >90% purity for key exosome markers.
- Complete Profile: Contains platelets, growth factors, and the full spectrum of plasma-derived exosomes.
Conclusion: From a Single Component to a Complete Therapy
Effective regenerative treatments require moving beyond a focus on just one component like platelets. The future lies in using the complete, combined power of all healing factors within a patient’s blood.
exosmart™ is the only point-of-care system designed to do this, giving clinicians a tool to deliver a truly complete, potent, and standardized autologous therapy.