exosmart
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PREPARATION & INSTRUCTIONS

From plasma
to preparation.

The exosmart preparation films, equipment checklist and device guidance in one place.

Start with the demonstration. Use the overview below to follow the sequence, and keep the current manufacturer’s Instructions for Use alongside your kit.

Watch the preparation ↓Before you begin
The exosmart hollow-fibre ultrafiltration device
EXOSMART™ · PREPARATION SUPPORT

INSIDE THE CONCENTRATION STEP

Plasma flows.
Its biology stays together.

Follow the plasma through the fibre lumens, then look closer at the membrane that separates the retained preparation from the permeate.

Exosmart circuit reconstruction above an enlarged hollow fibre. Gold represents plasma inside the lumen; biological components remain inside while permeate crosses the wall. Internal details and component sizes are illustrative. One fibre, enlarged

Plasma flows.

Reciprocal movement carries plasma along the inside of the hollow fibres.

Permeate leaves.

Water and permeable small solutes cross the membrane into the outer compartment and collection bag.

Retained components concentrate.

Platelets, vesicles and retained proteins remain in the preparation as its fluid volume falls.

VesiclesPlateletsSoluble signalsCarrier & regulatory proteinsMatrix-forming proteins

A SMALLER VOLUME, CONCENTRATED PLASMA BIOLOGY

From approximately 30 mL to 6 mL.

Retained components occupy a smaller fluid volume. The bars compare preparation volumes; individual component recovery and concentration vary.

Beginning · combined PRP + PPP≈30 mL
Final preparation≈6 mL

01 / WATCH

See the preparation in practice.

The exosmart preparation film shows the preparation workflow and collection of the concentrate.

UMA Academy recordings

Original exosmart preparation film · pause and replay as needed.

02 / UMA ACADEMY

A closer look at preparation.

PREPARATION RECORDING

exosmart instructional
and preparation video

The dedicated preparation edit from the UMA Academy collection.

Open preparation recording

Google Drive · MP4 · 1.45 GB source file

EXTENDED CLINICAL DEMONSTRATION

Preparation and
periorbital application

The full UMA Academy recording combines autologous secretome preparation with a demonstration of periorbital application.

Open full recording

Google Drive · MP4 · 3.02 GB source file

03 / BEFORE YOU BEGIN

Prepare your workspace.

Set out the equipment before starting the blood draw.

Use an aseptic workspace and check the kit packaging, expiry date and connections. The device and syringes are for a single patient and a single procedure.

  • 01
    exosmart sterile kit

    The hollow-fibre device and supplied components.

  • 02
    Plasma preparation system

    Your validated centrifugation method, with collection of both PRP and PPP.

  • 03
    Sterile Luer-lock syringes

    Two 20 mL syringes and a 10 mL syringe for collection, as specified in the device instructions.

  • 04
    Blood collection and aseptic supplies

    Prepare the collection materials and appropriate clinical waste disposal.

04 / THE SEQUENCE

Four stages. One preparation.

An overview to accompany the demonstration.

01

PRP + PPP

Prepare the plasma

Centrifuge using the selected plasma preparation system. Collect the PRP and PPP together; the standard workflow starts with approximately 30 mL of combined plasma.

02

DEVICE SET-UP

Assemble the circuit

Identify the plasma connections, hollow-fibre cartridge, air filter and filtrate bag. Follow the kit’s Instructions for Use for connection and priming.

03

APPROX. 3–5 MIN

Concentrate

Process the combined plasma through the hollow-fibre system. Water and permeable small solutes pass into the filtrate bag as the retained plasma components concentrate.

04

FINAL PREPARATION

Collect the preparation

Recover the concentrated autologous plasma using the collection sequence in the device instructions. The standard workflow yields approximately 6 mL. Collected volumes vary with the plasma preparation system and recovery; follow the device Instructions for Use.

For the operating sequence, syringe movements and product recovery, use the current manufacturer’s IFU supplied for your device.

05 / DOCUMENTS & SUPPORT

Instructions for Use and training

Device Instructions for Use

Request the current manufacturer’s document for your market and language.

Request the IFU

Practical training

Arrange a preparation session for your clinic or distribution team.

Arrange training

Clinical handbooks

Find specialty guidance for assessment, treatment planning and follow-up.

Find your handbook