/* typography.css */
/* The original brand typeface, with an editorial hierarchy shared by every page. */
body.es-page,.es-new-home,.es-testimonials{font-family:'Plus Jakarta Sans',Arial,Helvetica,sans-serif;font-weight:400;line-height:1.75}
body.es-page :is(button,input,select,textarea){font-family:inherit}
body.es-page :is(h1,h2,h3),.es-new-home :is(h2,h3),.es-testimonials>.es-wrap>h2{font-family:inherit;font-style:normal;font-weight:600;text-wrap:balance}
body.es-page h1{letter-spacing:-.045em;line-height:1.12}
body.es-page h2,.es-new-home h2{letter-spacing:-.035em;line-height:1.18}
body.es-page h3,.es-new-home h3{letter-spacing:-.02em;line-height:1.35}
body.es-page :is(p,li),.es-new-home :is(p,li){text-align:start;text-wrap:pretty}
body.es-page p,.es-new-home p{font-weight:400;line-height:1.75}
body.es-page .es-lead,.es-new-home .es-lead{line-height:1.65}
body.es-page p :is(strong,b),.es-new-home p :is(strong,b){font-weight:650;color:inherit}
body.es-page :is(cite,em),.es-new-home :is(cite,em){font-style:italic;font-weight:400}
body.es-page .es-eyebrow,.es-new-home .es-eyebrow{font-style:normal;line-height:1.5;letter-spacing:.13em!important}
body.es-page .es-section>.es-wrap>p:not(.es-eyebrow){max-width:72ch}
body.es-page :is(.sys-source,.xp-source,.es-note){line-height:1.7}
body.es-page :is(.sys-assay-table,.xp-assay,.xp-study-facts){font-variant-numeric:tabular-nums}
body.es-page .xp-hero h1{font-size:clamp(42px,4.7vw,64px);line-height:1.12;letter-spacing:-.04em}
body.es-page .xp-text-hero h1{font-size:clamp(44px,5.1vw,70px)}
body.es-page .sys-hero h1{font-size:clamp(44px,5vw,68px);line-height:1.1;letter-spacing:-.04em}
body.es-page :is(.xp-method-panel,.sys-bio-panel,.sys-lab-feature,.sys-marker,.sys-growth) h3{font-size:30px;line-height:1.25}
body.es-page .xp-contact-routes button strong{font-weight:600}
body.es-page .xp-timeline strong{font-weight:600;line-height:1.4;display:block}
body.es-page :is(.xp-three,.xp-timeline,.sys-workflow) p{line-height:1.7}
body.es-page .xp-study-list p{max-width:78ch}
body.es-page :is(.xp-book-feature,.xp-field-grid,.es-split,.sys-two)>*,.es-new-home .es-split>*{min-width:0}
/* Centred visual introduction: bounded lines and balanced headings, no clipped copy. */
body .elementor-2541 .elementor-element-d044727>.elementor-container{width:calc(100% - 80px)!important;max-width:1160px!important;margin-inline:auto}
body .elementor-2541 .elementor-element-d044727 .elementor-widget-heading{width:100%;max-width:100%;margin-inline:auto}
body .elementor-2541 .elementor-element-d044727 h2{max-width:1040px;margin:0 auto;font-size:clamp(34px,4.4vw,60px);font-weight:600;line-height:1.2;letter-spacing:-.035em;text-wrap:balance}
body .elementor-2541 .elementor-element-d044727 .elementor-widget-text-editor{max-width:900px;width:100%;margin-inline:auto;text-align:center}
body .elementor-2541 .elementor-element-d044727 .elementor-widget-text-editor p{white-space:normal;font-size:clamp(17px,1.5vw,20px);line-height:1.75;text-wrap:pretty;margin:0 auto 22px}
body .elementor-2541 :is(.elementor-element-1accf15,.elementor-element-828a952,.elementor-element-f5f17e7,.elementor-element-5fd6fa3,.elementor-element-fd1d184,.elementor-element-2f8a946) strong{font-weight:650;color:inherit}
/* The explanation below the film uses a comfortable reading column. */
body .elementor-2541 .elementor-element-2d6b42b>.elementor-widget-container{max-width:900px;margin:36px auto 26px!important}
body .elementor-2541 .elementor-element-2d6b42b p{font-size:17px;line-height:1.85;text-align:left;text-wrap:pretty;margin:0 0 24px;letter-spacing:0;color:#42576a}
body .elementor-2541 .elementor-element-2d6b42b p:first-child{font-size:19px;line-height:1.75;color:#21394d}
body .elementor-2541 .elementor-element-2d6b42b strong{font-weight:650;color:#18364e}
body .elementor-2541 .elementor-element-2d6b42b cite{font-style:italic}
@media(max-width:680px){
 body.es-page .xp-hero h1 br{display:block}
 body.es-page{font-size:16px}
 body.es-page :is(.xp-hero,.xp-text-hero) h1{font-size:clamp(36px,10vw,44px);line-height:1.14;letter-spacing:-.035em}
 body.es-page .sys-hero h1{font-size:clamp(38px,10.6vw,46px);line-height:1.12}
 body.es-page h2,.es-new-home h2{font-size:clamp(30px,8.2vw,36px);line-height:1.22;letter-spacing:-.03em}
 body.es-page :is(.xp-method-panel,.sys-bio-panel,.sys-lab-feature,.sys-marker,.sys-growth) h3{font-size:26px}
 body.es-page .es-lead,.es-new-home .es-lead{font-size:19px;line-height:1.7}
 body .elementor-2541 .elementor-element-d044727>.elementor-container{width:calc(100% - 40px)!important}
 body .elementor-2541 :is(.elementor-element-5fd6fa3,.elementor-element-fd1d184,.elementor-element-2f8a946) p{font-size:16px;line-height:1.75;max-width:100%;text-wrap:pretty}
 body .elementor-2541 .elementor-element-2d6b42b p,body .elementor-2541 .elementor-element-2d6b42b p:first-child{font-size:16px;line-height:1.8}
 body .elementor-2541 .elementor-element-2d6b42b>.elementor-widget-container{margin-top:26px!important}
}

/* refinement.css */
/* Exosmart editorial refinement. All rules are scoped away from the approved opening. */
.refined-page{--es-ink:#122f43;--es-muted:#526777;--es-blue:#286c94;--es-pale:#f2f6f7;--es-line:#d7e1e5}
.refined-page .es-wrap{width:min(1184px,calc(100% - 96px))}
body.refined-page.es-page{font-size:16px}
.refined-page .es-new-home{font-size:16px}
.refined-page :is(.es-new-home,.es-page) p{line-height:1.75}
.refined-page .es-section{padding:88px 0}
.refined-page.es-page h2,.refined-page .es-new-home h2{font-size:clamp(32px,3.35vw,46px);line-height:1.16;letter-spacing:-.04em;margin-bottom:28px}
.refined-page.es-page .es-lead,.refined-page .es-new-home .es-lead{font-size:20px;line-height:1.65}
.refined-page .es-eyebrow{font-size:10px!important;letter-spacing:.15em!important;margin-bottom:19px!important}
.refined-page .es-link{font-size:14px;padding:10px 0;gap:22px;text-underline-offset:5px}
.refined-page .es-link>span{transition:transform .2s}
.refined-page .es-link:hover>span{transform:translate(2px,-2px)}
.refined-page .es-button{padding:15px 22px;min-height:50px;border-radius:4px;font-size:13px;transition:background .2s,box-shadow .2s}
.refined-page .es-button:hover{box-shadow:0 6px 20px #12334719}
.refined-page .es-split{gap:72px}
/* One alignment line for logo, page titles and page content. */
.refined-page .es-header{width:min(1184px,calc(100% - 96px));max-width:none;padding:25px 0;min-height:95px;border-bottom:0;gap:36px}
.refined-page .es-header img{display:block;width:168px;height:auto}
.refined-page .es-header nav{gap:30px}
.refined-page .es-header nav a{font-size:13px;padding:10px 0;position:relative}
.refined-page .es-header nav a[aria-current]:after{content:'';position:absolute;bottom:2px;height:2px;background:#5f9fbd;left:0;right:0}
/* Homepage: a product spread, matched clinical cards, and a visual library. */
.refined-page .es-new-home #system .es-split{grid-template-columns:1.08fr 1fr;align-items:center;gap:86px}
.refined-page .es-new-home #system h2{max-width:530px}
.refined-page .es-new-home .es-product{border:0;border-radius:6px;padding:40px 30px 28px;background:radial-gradient(ellipse at 50% 45%,#fff 15%,#eaf1f4 90%);position:relative}
.refined-page .es-new-home .es-product img{height:470px;filter:drop-shadow(12px 20px 18px #183c4814)}
.refined-page .es-facts{gap:36px;margin:28px 0;padding-top:22px}
.refined-page .es-facts strong{font-size:20px}.refined-page .es-facts span{font-size:11px}
.ref-section-intro{display:grid;grid-template-columns:1fr 1fr;gap:72px;align-items:end;margin-bottom:38px}
.ref-section-intro h2,.ref-section-intro>.es-lead{margin-bottom:0!important}
.refined-page .ref-section-intro>.es-lead{font-size:17px;max-width:52ch}
.refined-page .es-new-home .es-app-grid{gap:24px;margin-top:0;align-items:stretch}
.refined-page .es-new-home .es-application{background:#fff;border-radius:6px;overflow:hidden;display:flex;flex-direction:column;box-shadow:0 8px 32px #16394e06}
.refined-page .es-new-home .es-photo{border-radius:0;margin:0}
.refined-page .es-new-home .es-photo img{aspect-ratio:1;transition:transform .5s ease}
.refined-page .es-new-home .es-application>div:last-child{padding:24px 23px 22px;flex:1;border-top:3px solid #98c0d0}
.refined-page .es-new-home .es-application h3{font-size:19px!important;line-height:1.35;min-height:52px;gap:16px}
.refined-page .es-new-home .es-application h3>span{flex-shrink:0;font-size:18px;color:#397698}
.refined-page .es-new-home .es-application p{font-size:13px;margin:13px 0 0;line-height:1.65}
.refined-page .es-new-home .es-section-end{margin-top:22px}
.refined-page .es-new-home #science{background:#102c40}
.refined-page .es-new-home #science>.es-wrap{display:grid;grid-template-columns:1fr 1fr;column-gap:72px}
.refined-page .es-new-home #science>.es-wrap>.es-eyebrow{grid-column:1/-1}
.refined-page .es-new-home #science>.es-wrap>h2{grid-column:1}
.refined-page .es-new-home #science .es-split{display:contents}
.refined-page .es-new-home #science .es-split>div:first-child{grid-column:1}
.refined-page .es-new-home #science .es-layers{grid-column:2;grid-row:2/4;align-self:start}
.refined-page .es-new-home .es-biology{height:auto;aspect-ratio:16/10;object-fit:cover;border-radius:5px;margin-top:30px}
.refined-page .es-new-home .es-dark p{color:#c4d5df}
.refined-page .es-new-home .es-layers summary{font-size:18px;gap:18px;font-weight:500}
.refined-page .es-new-home .es-layers details{padding:22px 0;border-color:#355163}
.refined-page .es-new-home .es-layers p{font-size:15px}
.ref-resources-grid{display:grid;grid-template-columns:.9fr 1.1fr;gap:64px;align-items:center}
.ref-book-display{display:grid;grid-template-columns:repeat(3,1fr);gap:12px;align-items:center;background:#edf2f3;padding:50px 30px 28px;text-decoration:none;min-width:0;border-radius:6px}
.ref-book-display img{display:block;width:100%;height:auto;box-shadow:5px 10px 16px #13324722;transform:translateY(-9px)}
.ref-book-display img:nth-child(2){transform:translateY(9px)}
.ref-book-display>span{grid-column:1/-1;font-size:9px;letter-spacing:.14em;color:#567080;margin-top:28px}
.ref-book-display b{display:block;color:#163c53;font-size:17px;letter-spacing:-.02em;font-weight:600;margin-top:8px}
.refined-page .ref-resources-grid .es-resource-list{margin:0}
.refined-page .ref-resources-grid .es-resource-list>a{grid-template-columns:80px 1fr 16px;gap:18px;padding:19px 0}
.refined-page .ref-resources-grid .es-resource-list h3{font-size:17px;margin-bottom:5px}
.refined-page .ref-resources-grid .es-resource-list p{font-size:13px}
.refined-page .es-new-home #resources>.es-wrap>.es-link{margin-top:24px}
.refined-page .es-new-home #connect{border-top:1px solid #d6e3e8;background:#eaf2f5}
.refined-page .es-new-home #connect .es-cta-links{gap:4px}
.refined-page .es-new-home #connect .es-cta-links a{padding:16px 0}
/* Page openings: quieter type, carefully framed imagery and meaningful breathing room. */
body.refined-page :is(.xp-hero,.sys-hero,.prep-hero,.faq-hero){background:#f2f6f7}
body.refined-page .xp-hero{padding:32px 0 62px}
body.refined-page .es-breadcrumb{font-size:11px;margin-bottom:32px;color:#607785}
body.refined-page .xp-hero-grid{grid-template-columns:1.1fr 1fr;gap:76px}
body.refined-page .xp-hero h1{font-size:clamp(40px,4vw,56px);letter-spacing:-.045em;line-height:1.12;margin-bottom:25px;text-wrap:balance}
body.refined-page .xp-text-hero{display:block;max-width:1000px}
body.refined-page .xp-text-hero h1{font-size:clamp(44px,4.6vw,64px);max-width:950px}
body.refined-page .xp-text-hero .es-lead{max-width:760px}
body.refined-page .xp-hero-grid figure img{border-radius:6px;box-shadow:0 14px 38px #173d4e09}
body.refined-page .xp-hero-grid figure figcaption{font-size:9px;margin-top:12px}
body.refined-page .xp-hero .es-lead{font-size:19px;max-width:54ch}
body.refined-page .xp-jump{padding:18px 0}
body.refined-page .xp-jump a{font-size:12px}
.ref-tissue-series{display:grid;grid-template-columns:repeat(3,1fr);gap:10px;align-items:center;padding:25px 0}
.ref-tissue-series a{position:relative;display:block;border-radius:5px;overflow:hidden;background:#0e263b;text-decoration:none;box-shadow:0 14px 30px #17354b13}
.ref-tissue-series a:nth-child(2){transform:translateY(25px)}
.ref-tissue-series img{width:100%;height:320px;display:block;object-fit:cover;object-position:center}
.ref-tissue-series span{display:block;padding:13px 8px;color:#e1edf4;text-align:center;font-size:10px;white-space:nowrap}
body.refined-page .ref-overview-hero{grid-template-columns:1.1fr 1fr;gap:56px}
body.refined-page .xp-field-row{padding:72px 0}
body.refined-page .xp-field-grid{grid-template-columns:1fr 1fr;gap:100px}
body.refined-page .xp-field-image img{border-radius:6px}
body.refined-page .xp-field-grid h2{font-size:40px}
body.refined-page .xp-topic-chips li{border-radius:3px;background:#f6f9fa;padding:6px 10px;font-size:11px}
body.refined-page .xp-three{gap:36px}
body.refined-page .xp-three article{padding-top:25px}
body.refined-page .xp-three article>span{margin-bottom:18px;font-size:10px}
body.refined-page .xp-three h3{font-size:21px}
body.refined-page .xp-three p{font-size:15px}
body.refined-page .xp-book-feature{grid-template-columns:.72fr 1.28fr;gap:90px}
body.refined-page .xp-cover{transform:rotate(-2deg);margin-inline:auto}
body.refined-page .xp-book-card>div{border-radius:5px;background:#e7eef1;padding:34px 54px}
body.refined-page .xp-book-card h3{font-size:21px;min-height:56px}
body.refined-page .xp-book-card .es-tag{font-size:10px;letter-spacing:.1em}
body.refined-page .xp-book-grid{gap:32px}
body.refined-page .xp-library-controls{border:1px solid var(--es-line);border-radius:5px;background:#f5f8f9;padding:28px}
body.refined-page .xp-resource{padding:27px 8px;transition:background .2s}
body.refined-page .xp-resource:hover{background:#f6f9fa}
body.refined-page .xp-resource h3{font-size:19px}
body.refined-page .xp-study-list{gap:0;border-top:1px solid var(--es-line)}
body.refined-page .xp-study-list article{border:0;border-bottom:1px solid var(--es-line);border-radius:0;padding:36px 32px}
body.refined-page .xp-study-list h3{font-size:27px}
body.refined-page .xp-method-panel{border-radius:0 0 6px 6px;padding:42px;gap:56px}
body.refined-page .xp-contact-layout{grid-template-columns:.85fr 1.15fr;gap:64px}
body.refined-page .xp-contact-routes{gap:0;border-top:1px solid var(--es-line)}
body.refined-page .xp-contact-routes button{border:0;border-bottom:1px solid var(--es-line);border-radius:0;padding:23px 20px;position:relative}
body.refined-page .xp-contact-routes button strong{font-size:17px}
body.refined-page .xp-contact-routes button[aria-pressed=true]{background:#eaf2f6;box-shadow:inset 3px 0 #3982a4}
body.refined-page .xp-enquiry{border:1px solid var(--es-line);border-radius:6px;background:#f5f8f9;padding:38px}
body.refined-page .xp input,body.refined-page .xp select,body.refined-page .xp textarea{border-color:#c0d0d9;border-radius:3px}
body.refined-page .sys-hero h1{font-size:clamp(42px,4.2vw,58px)}
body.refined-page .sys-hero-product img{height:480px}
body.refined-page .sys-hero-facts{margin-top:42px;padding:26px 0}
body.refined-page .sys-hero-facts strong{font-size:24px}
body.refined-page .sys-bio-panel{border-radius:0 0 6px 6px}
body.refined-page .sys-membrane,body.refined-page .sys-circuit{border-radius:6px}
body.refined-page .prep-hero h1{font-size:clamp(40px,4.2vw,58px)}
body.refined-page .prep-recording{border-radius:6px}
body.refined-page .faq-hero{padding:32px 0 48px}
body.refined-page .faq-hero h1{font-size:clamp(40px,4.4vw,60px);margin-bottom:20px}
body.refined-page .faq-layout{grid-template-columns:230px 1fr;gap:76px;padding-top:48px}
body.refined-page .faq-group h2{font-size:28px!important}
body.refined-page .faq-group summary{font-size:17px;padding-block:22px}
body.refined-page .faq-answer p{font-size:15px}
/* Footer turns the last screen into a calm, readable destination. */
body.refined-page .ref-footer{background:#edf3f5;border-top:1px solid #d8e3e8;padding:60px 0 24px}
.ref-footer-main{display:grid;grid-template-columns:1.8fr 1fr 1fr;gap:70px}
body.refined-page .ref-footer-brand img{display:block;width:170px;height:auto}
body.refined-page .ref-footer-brand p{font-size:14px;margin:22px 0 0;line-height:1.7}
body.refined-page .ref-footer nav{display:flex;flex-direction:column;gap:12px;margin:0;align-items:flex-start}
.ref-footer nav>span{font-size:9px;letter-spacing:.13em;color:#617989;margin-bottom:6px;font-weight:700}
body.refined-page .ref-footer a{font-size:13px}
body.refined-page .ref-footer a:hover{color:#267397}
.ref-footer-bottom{margin-top:50px;border-top:1px solid #d5e1e6;padding-top:22px;display:flex;align-items:center;justify-content:space-between}
body.refined-page .ref-footer-bottom nav{flex-direction:row;gap:24px}
@media(max-width:1050px){
 .refined-page .es-wrap,.refined-page .es-header{width:calc(100% - 64px)}
 .refined-page .es-new-home #system .es-split,.refined-page .es-split,.ref-section-intro,body.refined-page .xp-hero-grid,body.refined-page .xp-field-grid{gap:44px}
 .refined-page .es-new-home .es-product img{height:390px}
 .ref-resources-grid{gap:36px}.ref-book-display{padding:42px 22px 24px;gap:8px}
 body.refined-page .ref-overview-hero{gap:30px}.ref-tissue-series img{height:270px}
 .refined-page .es-header nav{gap:20px}
 body.refined-page .xp-field-grid h2{font-size:35px}
 body.refined-page .xp-enquiry{padding:28px}
 body.refined-page .xp-contact-layout{gap:36px}
}
@media(max-width:760px){
 .refined-page .es-wrap,.refined-page .es-header{width:calc(100% - 40px)}
 .refined-page .es-section{padding:58px 0}
 .refined-page.es-page h2,.refined-page .es-new-home h2{font-size:32px;margin-bottom:24px;line-height:1.19}
 .refined-page.es-page .es-lead,.refined-page .es-new-home .es-lead{font-size:18px;line-height:1.65}
 .refined-page .es-header{padding:20px 0;min-height:82px;gap:18px;flex-wrap:wrap}
 .refined-page .es-header img{width:150px}
 .refined-page .es-menu-toggle{display:block;font-family:inherit;font-size:12px;min-height:42px;padding:9px 16px}
 .refined-page .es-header nav{display:none;width:100%;flex-direction:column;align-items:stretch;gap:0}
 .refined-page .es-header nav.is-open{display:flex}.refined-page .es-header nav a{padding:13px 0}
 .refined-page .es-header nav a[aria-current]:after{right:auto;width:24px}
 .refined-page .es-new-home #system .es-split,.refined-page .es-split,.ref-section-intro,.ref-resources-grid,body.refined-page .xp-hero-grid,body.refined-page .xp-field-grid,body.refined-page .xp-contact-layout{grid-template-columns:1fr;gap:30px}
 .refined-page .es-new-home .es-product{padding:25px 20px 22px}.refined-page .es-new-home .es-product img{height:340px}
 .refined-page .es-new-home .es-app-grid{grid-template-columns:1fr;gap:24px}
 .refined-page .es-new-home .es-application>div:last-child{padding:20px}
 .refined-page .es-new-home .es-application h3{min-height:0;font-size:19px!important}
 .refined-page .es-new-home .es-application p{font-size:14px;margin-top:8px}
 .refined-page .es-new-home #science>.es-wrap{display:block}
 .refined-page .es-new-home #science .es-split{display:block}
 .refined-page .es-new-home #science .es-layers{margin-top:32px}
 .refined-page .es-new-home .es-biology{aspect-ratio:4/3}
 .refined-page .ref-resources-grid .es-resource-list>a{grid-template-columns:1fr 18px;gap:5px 16px;padding:20px 0}
 .refined-page .ref-resources-grid .es-tag{grid-column:1/-1;font-size:10px}
 .ref-book-display{padding:38px 25px 25px;gap:12px}
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